PBE
Invesco Biotechnology & Genome ETF
The Invesco Dynamic Biotechnology & Genome Portfolio ETF tracks a tiered equal-weighted index of companies principally engaged in biotechnology and genetic engineering.
US
EQUITY
Rules-Based
MANAGEMENT STYLE
$ 252.8 M
ASSETS UNDER MGMT
58 bp
EXPENSES
Fund Basics
| Inception date | Jun 23, 2005 |
| Regulation | Open-Ended Fund |
| Fund Website | link... |
| Distributions | Quarterly |
| Currency | USD |
| Holdings Transparency | Full |
| Derivatives-based | No |
| Options available | Yes |
| Currency hedged | No |
| Fund of funds | No |
Top 10 Holdings
Complete list +
| BIOGEN IDEC INC | 5.5 % |
| VERTEX PHARMACEUTICALS INC | 4.9 % |
| ILLUMINA INC | 4.8 % |
| INCYTE CORP | 4.8 % |
| AMGEN INC | 4.8 % |
| REGENERON PHARMACEUTICALS | 4.8 % |
| ROYALTY PHARMA PLC CLASS A | 4.7 % |
| GILEAD SCIENCES INC | 4.6 % |
| IONIS PHARMACEUTICALS, INC. | 4.2 % |
| UNITED THERAPEUTICS CORP | 3.7 % |
Constituent Breakdown
| Number of holdings | 28 |
| Herfindahl-Hirschman Index | 366 |
| Wgt avg mkt cap (mns) | $33,682 |
| Large cap (>$10bn) | 60.4% |
| Mid cap ($2-10bn) | 22.3% |
| Small cap (<$2bn) | 11.1% |
| Developed mkts. | 93.8% |
| Emerging mkts. | 0.0% |
Sector Breakdown
Country Exposure
 |
UNITED STATES | 93.8 % |
Historical Performance
Standardized Performance (as of 04/30/2026)
| YTD | 1 YR | 2 YR | 3 YR | 5 YR | 10 YR | 20 YR | Incep. | |
|---|---|---|---|---|---|---|---|---|
| Price Returns | -3.1% | 27.8% | 14.3% | 8.3% | 1.1% | 7.3% | 7.9% | 8.4% |
| Dividend Yield | -64.8% | -88.8% | -49.2% | 0.4% | 0.2% | 0.2% | 0.2% | 0.2% |
| Total Returns | -67.9% | -61.1% | -34.9% | 8.8% | 1.3% | 7.5% | 8.2% | 8.7% | Ann. Volatility | 121.9% | 70.7% | 52.1% | 126.5% | 99.3% | 72.7% | 54.6% | 53.6% |
Market Correlations
| versus... | Beta | R-squared |
| S&P 500 | 1.27 | 5% |
| MSCI EAFE | 0.69 | 2% |
| MSCI Emg Mkts | 0.78 | 4% |
Liquidity Measures
| Avg. volume (000) | 4 |
| ADV traded (mns) | $0 |
| Turnover | 0.1% |
| Avg. Bid/Ask (% of price) | 0.27% |
Technical Indicators
| 30d moving avg. (EMA) | $99.17 |
| Relative strength (RSI) | 18 |
| MACD/Signal | -11.59/-16.30 |
| Bollinger Bands (Upper/Lower) | $83.82/$78.33 |
| Short interest (% of AUM) | 0.0% |
Distributions
Top Ten Comparable ETFs only shown here. For an extended list become an Individual or Professional subscriber. Start your FREE trial
Comparable ETFs Based on Overlap
| Ticker | Fund Name | Overlap vs. PBE |
Expenses vs. PBE |
ALTAR Score™ vs. PBE |
|---|---|---|---|---|
| FBT | First Trust NYSE Arca Biotechnology Index Fund | 44.5% | -2 bp | -1.1% |
| BBH | VanEck Biotech ETF | 37.1% | -23 bp | +1.7% |
| IBB | iShares Biotechnology ETF | 36.8% | -13 bp | -3.7% |
| IBBQ | Invesco Nasdaq Biotechnology ETF | 34.8% | -39 bp | -2.8% |
| FTXH | First Trust Nasdaq Pharmaceuticals ETF | 33.1% | +2 bp | +4.6% |
| BBP | Virtus LifeSci Biotech Products ETF | 27.0% | +21 bp | -7.0% |
| XBI | State Street SPDR S&P Biotech ETF | 21.7% | -23 bp | -3.2% |
| GNOM | Global X Genomics & Biotechnology ETF | 21.6% | -8 bp | -6.4% |
| PJP | Invesco Pharmaceuticals ETF | 21.1% | -1 bp | +5.1% |
| FXH | First Trust Health Care AlphaDEX Fund | 20.8% | +4 bp | +2.4% |
Risk and Returns: PBE vs. Comps (1 YR)
Notes: Top 10 overlapping ETFs. Funds with insufficient history not shown. Some funds may overlap. Hover over data point for ticker symbol.
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Results & Estimates (USD)
| 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | 2026 | 2027 | ||
|---|---|---|---|---|---|---|---|---|---|
| Sales per share | -- | -- | -- | -- | -- | -- | -- | ||
| change (%) | -- | -- | -- | -- | -- | -- | -- | ||
| Earnings per share | -- | -- | -- | -- | -- | -- | -- | ||
| change (%) | -- | -- | -- | -- | -- | -- | -- | ||
| Dividends per share | -- | -- | -- | -- | -- | -- | -- | ||
| change (%) | -- | -- | -- | -- | -- | -- | -- | ||
| Book value per share | -- | -- | -- | -- | -- | -- | -- | ||
| change (%) | -- | -- | -- | -- | -- | -- | -- |
Return on Equity
Net Margins
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Valuation Metrics
| Fwd Est | 2025 | 2026 | 2027 | |
| Price-to-sales | --x | --x | --x | --x |
| Price-to-earnings | --x | --x | --x | --x |
| Price-to-cash flow | --x | --x | --x | --x |
| Price-to-growth | --x | --x | --x | --x |
| Price-to-book value | --x | --x | --x | --x |
| Yield | --% | --% | --x | --% |
Based on closing prices from 5/19/2026
Peer Group Comparison
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Historical Valuation Trends Sample data. Subscribe for access.
Notes: Based on adjusted historical results for current fund constituents. May differ from results achieved by past fund constituents. Max P/E of 100x.
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ETF Research Center Rating
3.1%
ALTAR SCORE™
13rd
PERCENTILE
AVOID
ETFRC RATING
There are 1,304 funds in the US Equity category with an average
ALTAR Score™ of 5.4% and a standard deviation
of 2.1%. PBE's ALTAR Score™ is approximately -1.1 standard
deviations above the category average. This places PBE in the 13rd percentile
among funds in the category.
Sell-Side Consensus
$102.74
PRICE TARGET
+27.8%
UPSIDE